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KMID : 0032220090210020213
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Annals of Dermatology
2009 Volume.21 No. 2 p.213 ~ p.216
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A Case of Churg-Strauss Syndrome
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Choi Ji-Hoon
Ahn In-Su
Lee Hee-Bong
Park Cheon-Wook
Lee Cheol-Heon
Ahn Hye-Kunng
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Abstract
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Churg-Strauss syndrome (CSS) or allergic granulomatosis angiitis is a rare primary vasculitic disease. CSS can be diagnosed by the presence of any four or more of the six criteria, which include asthma, eosinophilia greater than 10%, paranasal sinusitis, pulmonary infiltration, histological proof of vasculitis and mono- or poly-neuropathy. We report here on a 45-year-old male who developed erythematous macules, papules and hemorrhagic vesicles on both right extremities along with a tingling sensation and sacral pain. He has been suffering from recurrent allergic rhinitis and bronchial asthma for 6 months. The laboratory findings showed severe eosinophilia (22.3%), hyper-IgE and positivity for p-ANCA. On the histological examination of the hemorrhagic vesicle on the right lower leg, leukocytoclsatic vasulitis and many neutrophils and eosinophils around the cutaneous vessels were observed in the dermis.
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KEYWORD
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Churg-Strauss syndrome, CSS
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